A panel of leading European diabetes experts led by Professor Oliver Schnell from the Diabetes Research Institute in Munich has published a "Consensus Statement A European perspective" (1) on the benefits of self-monitoring of blood glucose values (SMBG). It recommends performing SMBG for all types of diabetes treatment approaches in order to achieve proper glucose control and values which are close to normal, without increasing the risk of hypoglycaemia. It emphasizes that optimal frequency and patterns of SMBG always depend on a variety of factors the type of diabetes, chosen therapy options, individually set targets of HbA1c as well as pre- and postprandial blood glucose values. "What is important to us is a homogeneous, structured and detailed approach to SMBG, which takes into account individual requirements", explains Professor Oliver Schnell. Innovatives blood glucose meters such as CONTOUR® from Bayer HealthCare Diabetes Care facilitate an individualized diabetes management, since they offer different levels of personalization and features such as meal markers or post-meal reminders, which support patients especially with postprandial testing.

The expert group evaluated existing scientific information and agreed upon practical recommendations for different groups of diabetes patients with regard to timings, frequencies and target values for SMBG, which go beyond current national and international guidelines. In general, diabetologists recommend an overall target of 6.5 percent for the HbA1c value for most patients. According to the consensus group, this target should be modified based on individual patient needs: For women who are pregnant or are planning to have a baby, a value of less than six percent is recommended. Patients with a high risk of hypoglycaemia or with unawareness of hypoglycaemia should not get over seven or 7.5 percent. Lower levels should be aimed for, but only if they can be achieved safely, since severe hypoglycaemia should be avoided in all patients to reduce the risk of severe complications.

With regard to overall targets for preprandial blood glucose, a value of less than six mmol/L respectively 108 mg/dL is the average. This target may be modified for individual patients like children, "high-risk" patients with known coronary artery disease or severe hypoglycaemia as well as pregnant women. The value for postprandial blood glucose should not exceed 7.8 mmol/L respectively 140 mg/dL. Here, testing is advised to be performed two hours after the meal and stressed as one of the key elements of optimal SMBG.

Also the recommended measuring frequency and timing depends on individual conditions such as the patient's treatment regimen. Experts differentiate between six patients' groups. Newly diagnosed Type 2 diabetics, for example, should test their blood glucose values three to five times a week to learn about the effects of lifestyle and medications on their metabolism. Instead, patients undergoing an intensified insulin treatment as well as "high risk" patients should check their values several times a day, especially postprandial or at nighttimes. For those experiencing severe hypoglycaemia even an increased frequency of nocturnal testing is recommended.

As a general rule, the consensus paper states that individual glycaemic targets should always be agreed upon between patient and the healthcare professional. Discussing the current results are advised to take place every three to six months, including pre and postprandial blood glucose values, HbA1c targets as well as lifestyle changes or circumstances complicating the effective control of diabetes, such as pregnancy, severe hypoglycaemic episodes or altered medication orders. "Changes in any of these factors should trigger an immediate adaptation of target values to ensure optimal treatment outcome and avoid late complications", says Professor Schnell.

About Bayer HealthCare Diabetes Care

Bayer HealthCare, Diabetes Care as part of the Medical Care Division supports customers in 100 countries and stands in a long tradition of leading the way in diabetes care product innovation since the introduction of CLINITEST reagent tablets in 1941. The face of diabetes care was changed in 1969 when the first portable blood glucose meter and test strips were introduced. Certain features of Bayer's blood glucose monitors such as No Coding technology and no interference from maltose and galactose make diabetes management easier. Today, Bayer HealthCare Diabetes Care offers an unparalleled choice in diabetes management systems and comprehensive support including education, tools and resources designed to simplify life with diabetes.

Bayer HealthCare Diabetes Care global headquarters is located in Tarrytown, New York, in the United States and operates as part of Bayer HealthCare LLC, a member of the worldwide Bayer HealthCare group. The Headquarters for the region Europe-MERA is located in Basel as part of Bayer Consumer Care AG, in Basel.

About Bayer HealthCare

The Bayer Group is a global enterprise with core competencies in the fields of health care, nutrition and high-tech materials. Bayer HealthCare, a subsidiary of Bayer AG, is one of the world's leading, innovative companies in the healthcare and medical products industry and is based in Leverkusen, Germany. The company combines the global activities of the Animal Health, Bayer Schering Pharma, Consumer Care and Medical Care divisions. Bayer HealthCare's aim is to discover and manufacture products that will improve human and animal health worldwide.

(1) O. Schnell et al., Diabetes, Stoffwechsel und Herz, 2009, 4, 285-289

Forward-Looking Statements

This release may contain forward-looking statements based on current assumptions and forecasts made by Bayer Group or subgroup management. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here.

Source: Bayer HealthCare